| Sunday, August 27 | |
|---|---|
| 4:00 pm – 8:30 pm | Registration in Chateau Liblice Foyer |
| 4:00 pm – 7:45 pm | Speaker presentation uploads in Lecture Hall |
| 6:00 pm – 7:30 pm | Reception in the Marble Hall |
| 7:30 pm – 7:45 pm | Introductory remarks in Lecture Hall |
| 7:45 pm – 8:45 pm | Tribute to Jan Svoboda (Robin Weiss, Jiri Hejnar, and others) |
| Monday, August 28 | |
|---|---|
| 8:00 am – 8:00 pm | Registration in Chateau Liblice Foyer |
| 8:00 am – 8:00 pm | Speaker presentation uploads in Lecture Hall |
| 7:30 am – 8:30 am | Breakfast in Chateau Liblice Restaurant |
| 7:30 am – 8:30 am | Poster set up in Marble Hall |
| 8:30 am – 9:15 am | Keynote Lecture 1 – Marc Sitbon: Retroviral envelopes and metabolic receptors: A fairy tale of humans, koalas and other mammals |
| Session 1 – Viral Life Cycle (part one, Early Events). Session chairs: Karen Beemon and Hung Fan |
|
| 9:20 am – 9:40 am | Norbert Bannert: Identification of a receptor binding site of the human endogenous retrovirus HERV-K(HML-2) |
| 9:40 am – 10:00 am | Monica Roth: Structural and sequencing studies involving gammaretroviral p12 chromatin tethering domain, integrase and human BET domains |
| 10:00 am – 10:20 am | Li Wu: N6-methyladenosine of HIV-1 RNA regulates viral replication: mechanisms and implications |
| 10:20 am – 10:30 am | David Přikryl: Superinfection interference and receptor usage of the newly emerging subgroup of avian leukosis virus. Short talk selected from abstracts |
| 10:30 am – 11:00 am | Break in Marble Hall Foyer |
| Session 1 – Viral Life Cycle (part two, Late Events, Expression and Latency). Session chairs: Karen Beemon and Hung Fan |
|
| 11:00 am – 11:20 am | Jun-ichi Sakuragi: The analysis of HIV-1 genome packaging by comparison of subtype sequences. |
| 11:20 am – 11:40 am | Dalibor Miklík: Accumulation of long-term transcriptionally active vectors in active promoters and enhancers. |
| 11:40 am – 12:00 am | Michaela Rumlová: Basic region of the M-PMV nucleocapsid protein plays a critical role in NC-RNA interactions. |
| 12:00 am – 12:20 pm | Jana Blažková: Effect of analytical treatment interruption of antiretroviral therapy on HIV reservoirs and immunological parameters |
| 12:30 pm – 2:00 pm | Lunch Buffet in Chateau Liblice Restaurant |
| Session 2 – Endogenous retroviruses. Session Chairs: Joachim Denner and Mary Poss |
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| 2:00 pm – 2:20 pm | Christine A. Kozak: Modification of mouse and human endogenous retroviruses by deletions of coding region segments flanked by short direct repeats |
| 2:20 pm – 2:40 pm | Daniel Elleder: Discovery of rare endogenous retroviruses |
| 2:40 pm – 3:00 pm | Robert Gifford: Genomic and evolutionary characteristics of novel retroviral lineages identified by phylogenetic screening of 234 vertebrate genomes |
| 3:00 pm – 3:20 pm | Petr Svoboda: LTR-driven evolution of genes and gene expression programs in mammalian oocytes and zygotes |
| 3:20 pm – 3:40 pm | Tongguang Wang: RNA-seq reveals molecular events regulated by HERV-K in human stem cells |
| 3:40 pm – 4:15 pm | Break in Marble Hall Foyer |
| 4:15 pm – 6:00 pm | Poster Session in Marble Hall |
| 6:00 pm – 7:30 pm | Dinner in Chateau Liblice Restaurant |
| 8:00 pm – 9:30 pm | Wine Tasting in Chateau Liblice Wine Cellar |
| Tuesday, August 29 | |
|---|---|
| 8:00 am – 8:00 pm | Registration in Chateau Liblice Foyer |
| 8:00 am – 8:00 pm | Speaker presentation uploads in Lecture Hall |
| 7:30 am – 8:30 am | Breakfast in Chateau Liblice Restaurant |
| Session 3 – Restriction Factors and Accessory Proteins. Session Chairs: Patrick Green and Luigi Chieco-Bianchi |
|
| 8:30 am – 8:50 am | Donna D’Agostino: Small noncoding RNAs in HTLV-1-infected cells |
| 8:50 am – 9:10 am | Jaquelin M. Dudley: In vivo retroviral replication suggests interactions with multiple APOBEC family members |
| 9:10 am – 9:30 am | Masaaki Miyazawa: Mouse APOBEC3 disrupts proteolytic autoprocessing of retroviral gag-pol precursors through direct binding to the protease domain |
| 9:30 am – 9:50 am | Stanislav Indik: Reverse transcriptase of mouse mammary tumor virus does not allow a high level of deamination by APOBEC3 proteins |
| 9:50 am – 10:00 am | Saina Beitari: HIV-1 antagonizes SERINC5. Short talk selected from abstracts. |
| 10:00 am – 10:30 am | Break in Marble Hall Foyer |
| 10:30 am – 10:50 am | Yoshinao Kubo: Rab3A, a small GTP-binding protein, is required for virion formation of murine leukemia virus |
| 10:50 am – 11:10 am | David Rekosh: REV-RRE functional activity differs substantially among primary HIV-1 isolates |
| 11:10 am - 11:30 am | Carsten Münk: Human APOBEC3H forms a barrier for cross species transmission of SIV of chimpanzee to humans |
| 11:30 am – 11:50 am | Anna Maria Passos-Castilho: nucleophosmin and nucleolin interact with bovine immunodeficiency virus rev protein and facilitate viral replication |
| 11:50 am – 12:10 pm | Amanda Panfil: Stability of the HTLV-1 antisense-derived protein, HBZ, is regulated by the E3 ubiquitin ligase Ubr5. Short talk selected from abstracts |
| 12:10 pm – 1:30 pm | Lunch Buffet in Chateau Liblice Restaurant |
| 1:30 pm – 7:00 pm | Free afternoon, trips (Škoda Cars in Mladá Boleslav, Antonín Dvořák in Nelahozeves, Brewery in Lobeč, Castle Bezděz) |
| 7:00 pm – 8:30 pm | Dinner in Chateau Liblice Restaurant |
| 8:30 pm – 9:15 pm | Keynote Lecture 2 – Karen Beemon: Avian retroviruses. RNA processing and cancer |
| Wednesday, August 30 | |
|---|---|
| 8:00 am – 8:00 pm | Registration in Chateau Liblice Foyer |
| 8:00 am – 8:00 pm | Speaker presentation uploads in Lecture Hall |
| 7:30 am – 8:30 am | Breakfast in Chateau Liblice Restaurant |
| 8:30 am – 9:15 am | Keynote lecture 3 – Charles R.M. Bangham: HTLV-1: persistence and pathogenesis |
| Session 4 – Immunology. Session Chairs: Kim Hasenkrug and Ivan Hirsch |
|
| 9:20 am – 9:40 am | Ulf Dittmer: The dose of retroviral infection determines the induction of anti-viral NK cell responses |
| 9:40 am – 10:00 am | Susan R. Ross: The Alr locus and its role in sensing retroviruses and retroelements |
| 10:00 am – 10:10 am | Joachim Denner: Retroviruses are immunosuppressive: role of the transmembrane envelope proteins |
| 10:10 am – 10:30 am | Kathrin Sutter: Improved effector functions of Friend Retrovirus-specific CD8+ T cells mediated by IFNα subtypes-activated DCs |
| 10:30 am – 10:50 am | Shin-nosuke Takeshima: CNTN3 rs110616206, MHC class III rs29026690 and MHC class I rs17872126 associated with the development of BLV infection determined by a GWAS |
| 10:50 am – 11:30 am | Break in Marble Hall Foyer |
| Session 5 – Pathogenesis. Session Chairs: Charles Bangham and Masaki Miyazawa |
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| 11:30 am – 11:50 am | James C. Neil. Targeting the runx genes: from retroviral mutagenesis to allosteric inhibitors |
| 11:50 am – 12:10 pm | Mary Poss: Do endogenous retroviruses contribute to LGL leukemia? |
| 12:10 pm – 12:30 pm | Mario L. Santiago: Unraveling HIV-1, microbe and host interactions in primary intestinal CD4+ T cells by transcriptomic profiling |
| 12:30 pm – 12:50 pm | Marta Garcia-Montojo: Human endogenous retrovirus K is more active in the blood of amyotrophic lateral sclerosis patients and can be targeted by antiretroviral therapy |
| 12:50 pm – 1:10 pm | Myoung-Hwa Lee: Transgenic mouse model of human endogenous retrovirus-K for studying the pathogenesis of amyotrophic lateral sclerosis |
| 1:10 pm – 2:30 pm | Lunch Buffet in Chateau Liblice Restaurant |
| Session 6 – Vaccines, Therapeutics, and New Technologies. Session Chairs: Susan Ross and James Neil |
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| 2:30 pm – 2:50 pm | Yoko Aida: Development of a bovine leukemia virus vaccine targeting susceptible cattle |
| 2:50 pm – 3:10 pm | Joachim Denner: Do porcine endogenous retroviruses (PERVs) pose a risk for xenotransplantation? |
| 3:10 pm – 3:30 pm | Marie-Luise Hammarskjold: Studies of lentiviral vector mediated antisense RNA inhibition reveals specific interactions between the rev/rre pathway and the adar editing machinery |
| 3:30 pm – 3:50 pm | Wibke Bayer: Advanced flow cytometric analysis of Friend virus infected target cells in mice |
| 3:50 pm – 4:10 pm | Closing remarks |
| 4:10 pm – 4:20 pm | Masaki Miyazawa: 30th International Workshop on Retroviral Pathogenesis in Kobe |
| 4:20 pm – 6:00 pm | Free Time, Discussions |
| 6:00 pm – 7:30 pm | Gala Dinner in Chateau Liblice Restaurant |
| 7:30 pm – ?? | Beer, Wine and Barbecue on the Terrace |
| Thursday, August 31 | |
|---|---|
| 6:30 am – 10:00 am | Breakfast in Chateau Liblice Restaurant |
| 6:30 am – 12:00 am | Departure. Schedule of shuttle buses will be provided soon |
| Posters (Monday, August 28, 4:00 pm – 6:00 pm, Marble Hall) | |
|---|---|
| Norbert Bannert | No significant HTLV seroprevalence in german people who inject drugs |
| Saina Beitari | HIV-1 Env antagonizes SERINC5 |
| Vicenzo Ciminale | Effects of Rex and cell division on HTLV-1 expression |
| Joachim Denner | Characterisation of koala retroviruses (KoRV) in European zoos and generation of a vaccine |
| Tara Doucet-O´Hare | Activation of a human endogenous retrovirus in a neurodevelopmental tumor and modulation by ouabain |
| Laurie Gray | HERV-K RcRE-like RNA elements present within some human genes function with HIV-1 Rev |
| Tomáš Hron | Insight into the epigenetic landscape of currently endogenizing gammaretrovirus present in the mule deer (Odocoileus hemionus) genome |
| Hongping Jin | Establish a humanized mouse model for testing a potent anti-HIV agent, nullbasic, in vivo |
| Anna Koslová | Rous sarcoma virus host range extension is coupled with Env-activating mutations |
| Michaela Madleňáková | Role of heme-induced redox stress in HIV-1 latency and cure |
| Claude Marchand | Identification of the nuclear/nucleolar import and nuclear export signals of the jembrana disease virus rev protein |
| Amanda R. Panfil | Stability of the HTLV-1 antisense derived protein, HBZ, is regulated by the E3 ubiquitin ligase, UBR5 |
| Vladimír Pečenka | HRAS, EGFR, RON and MET are recurrent targets of insertional mutagenesis in MAV-2 retrovirus-induced hepatocellular carcinomas, intrahepatic cholangiocarcinomas and hepatic hemangiosarcomas |
| David Přikryl | Superinfection interference and receptor usage of the newly emerging subgroup of avian leukosis virus |
| Filip Šenigl | Mapping somatic hypermutation susceptibility across the genome |
| Kateřina Trejbalová | DNA hypomethylation and aberrant expression of the human endogenous retrovirus ERVWE1/syncytin-1 in seminomas |
| Anne-Marie W. Turner | Profiling the chromatin state of HIV latency |
| Girish N. Vyas | Immune tolerance at the B cell level may underlie the pathogenesis of universally persistent HIV infection, a provocative concept |